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Shipping James or Lily with any DE character requires you to ignore their morals and ideologies against the pure blood DE characters to make it work. You would have to change everything about them.
Lily and James died for their son. They most likely knew the risk of having a baby, getting married, staying together but they did it anyway. James, a pure blood wizard put a target on his own back just because he was in love with a muggle born woman. Lily already had a target on her back when she came to Hogwarts.
These DE characters can be down right sadistic and evil and some ppl will still ship these characters. In reality these characters would kill each other on sight. And some will say "it's all fake anyway, let people ship" but that's the problem
Fiction relates to reality. Stories, poems, movies are all related to real situations, people, places and ideas, that's why some people can see themselves in certain stories. And by making these problematic ships, some ppl think it's cool and okay to let these situations happen irl.
It's not just shipping, it's an idea that could turn into action.